olivetolic acid
- Product Name
- olivetolic acid
- CAS No.
- 491-72-5
- Chemical Name
- olivetolic acid
- Synonyms
- Olivetolcarboxylic acid;2,4-Dihydroxy-6-pentylbenzoic acid;139400;olivetolic acid;olivanic acid powder 98%;Benzoic acid, 2,4-dihydroxy-6-pentyl-;Olivetolic acid 1000 μg/mL in Methanol
- CBNumber
- CB81340565
- Molecular Formula
- C12H16O4
- Formula Weight
- 224.25
- MOL File
- 491-72-5.mol
olivetolic acid Property
- Melting point:
- 143 °C
- Boiling point:
- 403.9±25.0 °C(Predicted)
- Density
- 1.237±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 3.41±0.34(Predicted)
- form
- Solid
- color
- Light Beige to Light Brown
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C12H16O4/c1-2-3-4-5-8-6-9(13)7-10(14)11(8)12(15)16/h6-7,13-14H,2-5H2,1H3,(H,15,16)
- InChIKey
- SXFKFRRXJUJGSS-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=C(CCCCC)C=C(O)C=C1O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 26282
- Product name
- Olivetolic Acid
- Packaging
- 25mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 26282
- Product name
- Olivetolic Acid
- Packaging
- 5mg
- Price
- $31
- Updated
- 2023/06/20
- Product number
- O533005
- Product name
- OlivetolicAcid
- Packaging
- 100mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- O533005
- Product name
- OlivetolicAcid
- Packaging
- 500mg
- Price
- $490
- Updated
- 2021/12/16
- Product number
- PXT0005334
- Product name
- OLIVETOLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.01
- Updated
- 2021/12/16
olivetolic acid Chemical Properties,Usage,Production
Uses
Olivetolic Acid is a precursor in the synthesis of primin and tetrahydrocannabinol.
Definition
ChEBI: A member of the class of benzoic acids that is salicylic acid in which the hydrogens ortho- and para- to the carboxy group are replaced by a pentyl and a hydroxy group, respectively.
Biosynthesis
Olivetolic acid (OLA) biosynthesis involves the condensation of one hexanoyl-CoA with three malonyl-CoAs by a type III PKS (tetraketide synthase) OLA synthase (C. sativa OLS; CsOLS) and an OLA cyclase (CsOAC), both enzymes were derived from the Cannabis species (C. sativa). Studies have achieved trace amount of OLA production in both E. coli and S. cerevisia[1]. Ma et al. find that Pseudomonas sp LvaE encoding a short-chain acyl-CoA synthetase can efficiently convert hexanoic acid to hexanoyl-CoA. The co-expression of the acetyl-CoA carboxylase, the pyruvate dehydrogenase bypass, the NADPH-generating malic enzyme, as well as the activation of peroxisomal β-oxidation pathway and ATP export pathway are effective strategies to redirect carbon flux toward OLA synthesis.
References
[1] Ma, J, Y. Gu, and P. Xu . "Biosynthesis of cannabinoid precursor olivetolic acid by overcoming rate-limiting steps in genetically engineered Yarrowia lipolytica." Cold Spring Harbor Laboratory(2021).
olivetolic acid Preparation Products And Raw materials
Raw materials
Preparation Products
olivetolic acid Suppliers
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View Lastest Price from olivetolic acid manufacturers
- Product
- olivetolic acid 491-72-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 3000kg
- Release date
- 2023-12-08
- Product
- olivetolic acid 491-72-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
- Product
- olivetolic acid 491-72-5
- Price
- US $1.00/KG
- Min. Order
- 100g
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2019-12-17